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Article

Phosphorylation and cellular function of the human Rpa2 N-terminus in the budding yeast Saccharomyces cerevisiae.

Experimental cell research - 1 Feb 2015

Ghospurkar Padmaja L, Wilson Timothy M, Liu Shengqin, Herauf Anna, Steffes Jenna, Mueller Erica N, Oakley Gregory G, Haring Stuart J

Abstract excerpt

Maintenance of genome integrity is critical for proper cell growth. This occurs through accurate DNA replication and repair of DNA lesions. A key factor involved in both DNA replication and the DNA damage response is the heterotrimeric single-stranded DNA (ssDNA) binding complex Replication Protein A (RPA). Although the RPA complex appears to be structurally conserved throughout eukaryotes, the primary amino acid...

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Identifiers

PMID: 25499885
DOI: 10.1016/j.yexcr.2014.12.002
PMCID: PMC4334453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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