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Article

Essential functions of the 32 kDa subunit of yeast replication protein A.

Nucleic acids research - 1 Apr 2009

Dickson Anne M, Krasikova Yulia, Pestryakov Pavel, Lavrik Olga, Wold Marc S

Abstract excerpt

Replication protein A (RPA) is a heterotrimeric (70, 32 and 14 kDa subunits), single-stranded DNA-binding protein required for cellular DNA metabolism. All subunits of RPA are essential for life, but the specific functions of the 32 and 14 kDa subunits remains unknown. The 32 kDa subunit (RPA2) has multiple domains, but only the central DNA-binding domain (called DBD D) is essential for life in Saccharomyces...

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Identifiers

PMID: 19244309
DOI: 10.1093/nar/gkp090
PMCID: PMC2673435

Genes

RPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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