Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response.

Nucleic acids research - 1 Oct 2000

Brush G S, Kelly T J

Abstract excerpt

The checkpoint mechanisms that delay cell cycle progression in response to DNA damage or inhibition of DNA replication are necessary for maintenance of genetic stability in eukaryotic cells. Potential targets of checkpoint-mediated regulation include proteins directly involved in DNA metabolism, such as the cellular single-stranded DNA (ssDNA) binding protein, replication protein A (RPA). Studies in Saccharomyces...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Fungal
Share to Cyclin B
Share to DNA-Activated Protein Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Single-Stranded

Share to Dose-Response Relationship, Radiation

Share to Glycosyltransferases

Share to Hydroxyurea

Share to Replication Protein A

Source

Open in PubMed Open full text

Identifiers

PMID: 11000264
DOI: 10.1093/nar/28.19.3725
PMCID: PMC110765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response.PMID 11000264Read ↗

The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast.Semantic proximity Read ↗

Evidence of meiotic crossover control in Saccharomyces cerevisiae through Mec1-mediated phosphorylation of replication protein A.Semantic proximity Read ↗

Functions of human replication protein A (RPA): From DNA replication to DNA damage and stress responsesSemantic proximity Read ↗

In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling.Semantic proximity Read ↗

NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapseSemantic proximity Read ↗

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.Semantic proximity Read ↗

Proteins in the nutrient-sensing and DNA damage checkpoint pathways cooperate to restrain mitotic progression following DNA damage.Semantic proximity Read ↗

Phosphorylation and cellular function of the human Rpa2 N-terminus in the budding yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.Semantic proximity Read ↗

Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway.Semantic proximity Read ↗

RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.Semantic proximity Read ↗

Replication checkpoint protein Mrc1 is regulated by Rad3 and Tel1 in fission yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.