Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation.

doi:10.1200/JCO.2013.53.2820

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 May 2014

Finch Amy P M, Lubinski Jan, Møller Pål, Singer Christian F, Karlan Beth, Senter Leigha, Rosen Barry, Maehle Lovise, Ghadirian Parviz, Cybulski Cezary, Huzarski Tomasz, Eisen Andrea, Foulkes William D, Kim-Sing Charmaine, Ainsworth Peter, Tung Nadine, Lynch Henry T, Neuhausen Susan, Metcalfe Kelly A, Thompson Islay, Murphy Joan, Sun Ping, Narod Steven A

Abstract excerpt

PURPOSE: The purposes of this study were to estimate the reduction in risk of ovarian, fallopian tube, or peritoneal cancer in women with a BRCA1 or BRCA2 mutation after oophorectomy, by age of oophorectomy; to estimate the impact of prophylactic oophorectomy on all-cause mortality; and to estimate 5-year survival associated with clinically detected ovarian, occult, and peritoneal cancers diagnosed in the cohort....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Fallopian Tube Neoplasms

Share to North America

Share to Ovariectomy

Share to Peritoneal Neoplasms

Share to Proportional Hazards Models

Share to Registries

Source

Open in PubMed Open full text

Identifiers

PMID: 24567435
DOI: 10.1200/JCO.2013.53.2820
PMCID: PMC4026578

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation.PMID 24567435Read ↗

Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation.Semantic proximity Read ↗

Effect of Oophorectomy on Survival After Breast Cancer in BRCA1 and BRCA2 Mutation Carriers.Semantic proximity Read ↗

Risk-reducing salpingo-oophorectomy: a meta-analysis on impact on ovarian cancer risk and all cause mortality in BRCA 1 and BRCA 2 mutation carriers.Semantic proximity Read ↗

Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations.Semantic proximity Read ↗

Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation.Semantic proximity Read ↗

Incidence of peritoneal cancer after oophorectomy among BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.Semantic proximity Read ↗

Risk-reducing salpingo-oophorectomy and breast cancer risk in BRCA1 or BRCA2 mutation carriers: A systematic review and meta-analysis.Semantic proximity Read ↗

Pathologic findings at risk-reducing salpingo-oophorectomy: primary results from Gynecologic Oncology Group Trial GOG-0199.Semantic proximity Read ↗

Interventions to reduce the risk of ovarian and fallopian tube cancer: A European Menopause and Andropause Society Postition Statement.Semantic proximity Read ↗

A model for estimating ovarian cancer risk: application for preventive oophorectomy.Semantic proximity Read ↗

Risk-reducing bilateral salpingo-oophorectomy in women with BRCA1 or BRCA2 mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.