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Article

A prospective multicentric study of risk-reducing salpingo-oophorectomy in BRCA mutation patients.

Acta bio-medica : Atenei Parmensis - 31 Aug 2022

Loizzi Vera, Cicinelli Ettore, Del Vecchio Vittoria, Arezzo Francesca, Deromemaj Xheni, Kardhashi Anila, Paradiso Angelo, Legge Francesco, Natalicchio Maria Iole, Resta Leonardo, Resta Nicoletta, Loconte Daria Carmela, Cormio Gennaro

Abstract excerpt

BACKGROUND AND AIM OF THE WORK: BRCA1/2 are tumour-suppressor genes involved in DNA homologous recombination and ovarian cancer development. The study evaluated the risk of tumor cancer in women presenting the BRCA mutations. METHODS: Risk-reducing surgery (RRS) was performed in 100 patients carrying BRCA1 (aged between 30-73 years, median age was 51 years) and BRCA 2 mutation (aged between 36-70 years, median...

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Identifiers

PMID: 36043985
DOI: 10.23750/abm.v93i4.11695
PMCID: PMC9534247

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