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Article

The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.

The Journal of biological chemistry - 23 Jan 2015

Mlih Mohamed, Host Lionel, Martin Sophie, Niederhoffer Nathalie, Monassier Laurent, Terrand Jérôme, Messaddeq Nadia, Radke Michael, Gotthardt Michael, Bruban Véronique, Kober Frank, Bernard Monique, Canet-Soulas Emmanuelle, Abt-Jijon Francisco, Boucher Philippe, Matz Rachel L

Abstract excerpt

Src homology and collagen A (ShcA) is an adaptor protein that binds to tyrosine kinase receptors. Its germ line deletion is embryonic lethal with abnormal cardiovascular system formation, and its role in cardiovascular development is unknown. To investigate its functional role in cardiovascular d...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25488665
DOI: 10.1074/jbc.M114.597377
PMCID: PMC4303691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25488665-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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