Article
The role of cell adhesion molecules in Drosophila heart morphogenesis: faint sausage, shotgun/DE-cadherin, and laminin A are required for discrete stages in heart development.
Developmental biology - 1 Apr 1999
Haag T A, Haag N P, Lekven A C, Hartenstein V
Abstract excerpt
Heart development in the Drosophila embryo starts with the specification of cardiac precursors from the dorsal edge of the mesoderm through signaling from the epidermis. Cardioblasts then become aligned in a single row of cells that migrate dorsally. After contacting their contralateral counterparts, cardioblasts undergo a cytoskeletal rearrangement and form a lumen. Its simple architecture and cellular...
Topics
- Animals
- Cadherins
- Calcium
- Cell Adhesion
- Drosophila
- Drosophila Proteins
- Embryonic Development
- Gene Expression Regulation, Developmental
- Heart
- Immunohistochemistry
- Laminin
- Mesoderm
- Morphogenesis
- Neuropeptides
- Phenotype