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Article

The association of caveolae, actin, and the dystrophin-glycoprotein complex: a role in smooth muscle phenotype and function?

Canadian journal of physiology and pharmacology - 1 Oct 2005

Halayko Andrew J, Stelmack Gerald L

Abstract excerpt

Smooth muscle cells exhibit phenotypic and mechanical plasticity. During maturation, signalling pathways controlling actin dynamics modulate contractile apparatus-associated gene transcription and contractile apparatus remodelling resulting from length change. Differentiated myocytes accumulate abundant caveolae that evolve from the structural association of lipid rafts with caveolin-1, a protein with domains...

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PMID: 16333360
DOI: 10.1139/y05-107

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