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Article

Is lymphocyte adenosine a diagnostic marker of clinical malignant hyperthermia? A pilot study.

Critical care medicine - 1 Mar 2015

Bina Saiid, Capacchione John, Munkhuu Bayarsaikhan, Muldoon Sheila, Bünger Rolf

Abstract excerpt

OBJECTIVE: Malignant hyperthermia is a pharmacogenetic disorder typically triggered by potent inhalation anesthetics and/or the depolarizing muscle relaxant succinylcholine in malignant hyperthermia-susceptible individuals. Since lymphocytes express the same Ca channel mutation found in malignant hyperthermia-susceptible muscle, we investigated agonist-induced adenosine formation in lymphocytes as an index of...

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Identifiers

PMID: 25479114
DOI: 10.1097/CCM.0000000000000744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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