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European Malignant Hyperthermia Group 2025 guidelines for the investigation of malignant hyperthermia susceptibility.

British journal of anaesthesia - 1 Feb 2026

Rüffert Henrik, Gillies Robyn, Hopkins Philip M, Glahn Klaus P E, Johannsen Stephan, Kamsteeg Erik-Jan, Hellblom Anna, Stowell Kathryn, Bilmen Jonathan, Klincova Martina, Girard Thierry

Abstract excerpt

Since malignant hyperthermia (MH) was first described in 1960, the number of cases of this potentially life-threatening reaction to anaesthesia with fatal or serious outcomes has been markedly reduced thanks to continuous advances in knowledge about triggering, clinical course, and treatment. Another essential and evolving pillar of patient safety remains diagnostics, which serve to confirm or rule out suspected...

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PMID: 41478797
DOI: 10.1016/j.bja.2025.11.006

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