Article
[Malignant hyperthermia].
La Tunisie medicale - 1 Jul 2002
Bouhajja Béchir, Haddad Fayçal, Ben Ammar Mohamed Salah
Abstract excerpt
Malignant hyperthermia is a potentially fatal pharmacogenetic disease triggered by volatile anesthetics and/or succinylcholine. Dysregulation of intracellular calcium homeostasis is the trigger of the acute crisis. Malignant hyperthermia crisis correspond to an hypermetabolic state, which occurred acutely and interesting skeletal muscular cell. Early manifestations grouped tachycardia, tachypnea, masseter spasm,...
Topics
- Anesthesia, General
- Dantrolene
- Diagnosis, Differential
- Genetic Predisposition to Disease
- Humans
- Infusions, Intravenous
- Malignant Hyperthermia
- Muscle Relaxants, Central
- Neuromuscular Depolarizing Agents
- Prognosis
- Risk Factors