Article
[Modern diagnostic approaches to malignant hyperthermia susceptibility].
Anesteziologiia i reanimatologiia - 1 Jan 2000
Kazantseva A A, Lebedinskiĭ K M
Abstract excerpt
Malignant hyperthermia is a well-known rare life-threatening autosomal-dominant pharmacogenetic disease, The arti- cle deals with a halothane-caffeine contracture test. The test is a model of muscle reaction to triggers in-vitro and it is the "golden standard" for malignant hyperthermia susceptibility (MHS) diagnosis. Genetic analysis is less invasive, but its sensitivity is significantly lower. The review...
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