Article
Comparative analysis of in vitro contracture tests with ryanodine and a combination of ryanodine with either halothane or caffeine: a comparative investigation in malignant hyperthermia.
Acta anaesthesiologica Scandinavica - 1 Sept 2004
Bendahan D, Guis S, Monnier N, Kozak-Ribbens G, Lunardi J, Ghattas B, Mattei J-P, Cozzone P J
Abstract excerpt
BACKGROUND: The diagnosis of susceptibility to malignant hyperthermia (MH) is currently performed on muscle biopsies subjected to halothane-caffeine in vitro contracture tests (IVCTs). There is a consensus on our need to improve the diagnostic potential of IVCTs if we are to maximize the information available for research and diagnosis in MH. This study was designed as a pilot comparative study and we aimed at...
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