Article
Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells.
Mechanisms of ageing and development - 1 Oct 2013
Machado Ana Manuel Dantas, Desler Claus, Bøggild Sisse, Strickertsson Jesper A B, Friis-Hansen Lennart, Figueiredo Ceu, Seruca Raquel, Rasmussen Lene Juel
Abstract excerpt
Helicobacter pylori infection is an important factor for the development of atrophic gastritis and gastric carcinogenesis. However, the mechanisms explaining the effects of H. pylori infection are not fully elucidated. H. pylori infection is known to induce genetic instability in both nuclear and...
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