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Ultrasensitive Biosensors Detecting m6A in Blood: Achieving Early Screening and Typing of Tumors

29 Oct 2024

Abstract excerpt

N 6 -methyladenosine (m 6 A) modification is one of the most widespread RNA modifications in eukaryotes and is involved in cancer development and progression by regulating oncogene expression. Herein, a reticulated rolling circle amplification (RCA) cascade reaction was used to construct a novel electrochemical biosensor for ultrasensitive detection of m 6 A, employing ferrocene-tyramine (Fc-Tyr) molecules as...

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PMID: 39470316
DOI: 10.1021/acssensors.4c01875

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