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Article

Genetic influences on the acquisition and inhibition of fear.

International journal of psychophysiology : official journal of the International Organization of Psychophysiology - 1 Dec 2015

Wendt Julia, Neubert Jörg, Lindner Katja, Ernst Florian D, Homuth Georg, Weike Almut I, Hamm Alfons O

Abstract excerpt

As a variant of the Pavlovian fear conditioning paradigm the conditional discrimination design allows for a detailed investigation of fear acquisition and fear inhibition. Measuring fear-potentiated startle responses, we investigated the influence of two genetic polymorphisms (5-HTTLPR and COMT Val(158)Met) on fear acquisition and fear inhibition which are considered to be critical mechanisms for the etiology and...

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Share to Catechol O-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25455425
DOI: 10.1016/j.ijpsycho.2014.10.007

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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