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Article

Failure to extinguish fear and genetic variability in the human cannabinoid receptor 1.

Translational psychiatry - 25 Sept 2012

Heitland I, Klumpers F, Oosting R S, Evers D J J, Leon Kenemans J, Baas J M P

Abstract excerpt

Failure to extinguish fear can lead to persevering anxiety and has been postulated as an important mechanism in the pathogenesis of human anxiety disorders. In animals, it is well documented that the endogenous cannabinoid system has a pivotal role in the successful extinction of fear, most impor...

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Share to Conditioning, Psychological
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extinction, Psychological

Share to Receptor, Cannabinoid, CB1

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Source

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Identifiers

PMID: 23010766
DOI: 10.1038/tp.2012.90
PMCID: PMC3565211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23010766-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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