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Article

Big genes are big mutagen targets: a connection to cancerous, spherical cells?

Cancer letters - 28 Jan 2015

Parry Michele L, Ramsamooj Michael, Blanck George

Abstract excerpt

We determined the most commonly mutated genes in five cancer genome atlas (TCGA) datasets. Many of these genes were extraordinarily large, as are many cancer fusion gene partners. And many of these genes had cytoskeletal related functions. We further determined that these genes were distributed into high and low frequency mutation groups largely according to overall rate of gene-occurrence in the high and low...

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PMID: 25451318
DOI: 10.1016/j.canlet.2014.09.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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