Article

Cell shapes decode molecular phenotypes in image-based spatial proteomics

2025-05-16

Abstract excerpt

<h4>Summary</h4> The diversity of cellular and tissue structures can arise from a few basic cell shapes, which undergo various transformations based on biophysical constraints on cytoskeletal organization. While cellular geometry has been linked with selected biological processes such as polarity, signaling or morphogenesis, the orchestration of the whole proteome in association to cell shape is still poorly unde...

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Literature Corpus work: 5616a79e-e069-5009-b6c6-09cbbb541730
DOI: 10.1101/2025.05.13.653868

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