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Article

High plasma levels of soluble endothelial protein C receptor are associated with increased mortality among children with cerebral malaria in Benin.

The Journal of infectious diseases - 1 May 2015

Moussiliou Azizath, Alao Maroufou J, Denoeud-Ndam Lise, Tahar Rachida, Ezimegnon Sem, Sagbo Gratien, Amoussou Annick, Luty Adrian J F, Deloron Philippe, Tuikue Ndam Nicaise

Abstract excerpt

Loss of endothelial protein C receptor (EPCR) occurs at the sites of Plasmodium falciparum-infected erythrocyte sequestration in patients with or who died from cerebral malaria. In children presenting with different clinical syndromes of malaria, we assessed the relationships between endogenous plasma soluble EPCR (sEPCR) levels and clinical presentation or mortality. After adjustment for age, for treatment...

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PMID: 25425698
DOI: 10.1093/infdis/jiu661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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