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Could Soluble Endothelial Protein C Receptor Levels Recognize SARS-CoV2-Positive Patients Requiring Hospitalization?

Shock (Augusta, Ga.) - 1 Nov 2021

Vassiliou Alice G, Keskinidou Chrysi, Jahaj Edison, Gallos Parisis, Zacharis Alexandros, Athanasiou Nikolaos, Tsipilis Stamatios, Mastora Zafeiria, Dimopoulou Ioanna, Kotanidou Anastasia, Orfanos Stylianos E

Abstract excerpt

INTRODUCTION: The endothelial protein C receptor (EPCR) is a protein that regulates the protein C anticoagulant and anti-inflammatory pathways. A soluble form of EPCR (sEPCR) circulates in plasma and inhibits activated protein C (APC) activities. The clinical impact of sEPCR and its involvement in COVID-19 has not been explored. In this study, we investigated whether sEPCR levels were related to COVID-19...

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Identifiers

PMID: 33756504
DOI: 10.1097/SHK.0000000000001780
PMCID: PMC8518207

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