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Article

FOXO3A regulatory polymorphism and susceptibility to severe malaria in Gabonese children.

Immunogenetics - 1 Feb 2015

Nguetse Christian Ngouadjio, Kremsner Peter G, Velavan Thirumalaisamy P

Abstract excerpt

The clinical course of malaria varies between affected individuals and host genetic factors have been shown to influence the outcome of malaria. The role of FOXO3-driven pathway in modulating inflammatory responses, including mediation of distinct functions of regulatory T effector cell populations (Tregs) by the transcription factor FOXO3, has recently been recognized. We aimed to study possible associations of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25421486
DOI: 10.1007/s00251-014-0816-z

Genes

FOXO3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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