Article
Fine-mapping additive and dominant SNP effects using group-LASSO and fractional resample model averaging.
Genetic epidemiology - 1 Feb 2015
Sabourin Jeremy, Nobel Andrew B, Valdar William
Abstract excerpt
Genomewide association studies (GWAS) sometimes identify loci at which both the number and identities of the underlying causal variants are ambiguous. In such cases, statistical methods that model effects of multiple single-nucleotide polymorphisms (SNPs) simultaneously can help disentangle the observed patterns of association and provide information about how those SNPs could be prioritized for follow-up...
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