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Article

Prioritizing genetic variants in GWAS with lasso using permutation-assisted tuning.

Bioinformatics (Oxford, England) - 1 Jun 2020

Yang Songshan, Wen Jiawei, Eckert Scott T, Wang Yaqun, Liu Dajiang J, Wu Rongling, Li Runze, Zhan Xiang

Abstract excerpt

MOTIVATION: Large scale genome-wide association studies (GWAS) have resulted in the identification of a wide range of genetic variants related to a host of complex traits and disorders. Despite their success, the individual single-nucleotide polymorphism (SNP) analysis approach adopted in most current GWAS can be limited in that it is usually biologically simple to elucidate a comprehensive genetic architecture...

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PMID: 32246825
DOI: 10.1093/bioinformatics/btaa229
PMCID: PMC7320616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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