Sparse multitask group Lasso for genome-wide association studies.

Abstract excerpt

A critical hurdle in Genome-Wide Association Studies (GWAS) involves population stratification, wherein differences in allele frequencies among subpopulations within samples are influenced by distinct ancestry. This stratification implies that risk variants may be distinct across populations with different allele frequencies. This study introduces Sparse Multitask Group Lasso (SMuGLasso) to tackle this challenge....

Topics

• Genome-Wide Association Study
• Polymorphism, Single Nucleotide
• Humans
• Linkage Disequilibrium
• Breast Neoplasms
• Arabidopsis
• Computational Biology