Article
Gamma-tubulin regulates the anaphase-promoting complex/cyclosome during interphase.
The Journal of cell biology - 9 Aug 2010
Nayak Tania, Edgerton-Morgan Heather, Horio Tetsuya, Xiong Yi, De Souza Colin P, Osmani Stephen A, Oakley Berl R
Abstract excerpt
A cold-sensitive gamma-tubulin allele of Aspergillus nidulans, mipAD159, causes defects in mitotic and cell cycle regulation at restrictive temperatures that are apparently independent of microtubule nucleation defects. Time-lapse microscopy of fluorescently tagged mitotic regulatory proteins reveals that cyclin B, cyclin-dependent kinase 1, and the Ancdc14 phosphatase fail to accumulate in a subset of nuclei at...
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