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Article

dRYBP counteracts chromatin-dependent activation and repression of transcription.

PloS one - 1 Jan 2014

Fereres Sol, Simón Rocío, Mohd-Sarip Adone, Verrijzer C Peter, Busturia Ana

Abstract excerpt

Chromatin dependent activation and repression of transcription is regulated by the histone modifying enzymatic activities of the trithorax (trxG) and Polycomb (PcG) proteins. To investigate the mechanisms underlying their mutual antagonistic activities we analyzed the function of Drosophila dRYBP, a conserved PcG- and trxG-associated protein. We show that dRYBP is itself ubiquitylated and binds ubiquitylated...

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Share to Chromatin
Share to Epistasis, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25415640
DOI: 10.1371/journal.pone.0113255
PMCID: PMC4240632

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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