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Article

Widespread genetic epistasis among cancer genes.

Nature communications - 19 Nov 2014

Wang Xiaoyue, Fu Audrey Q, McNerney Megan E, White Kevin P

Abstract excerpt

Quantitative genetic epistasis has been hypothesized to be an important factor in the development and progression of complex diseases. Cancers in particular are driven by the accumulation of mutations that may act epistatically during the course of the disease. However, as cancer mutations are un...

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PMID: 25407795
DOI: 10.1038/ncomms5828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25407795-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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