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Article

Gene-gene interactions in gastrointestinal cancer susceptibility.

Oncotarget - 11 Oct 2016

Kim Jineun, Yum Seoyun, Kang Changwon, Kang Suk-Jo

Abstract excerpt

Cancer arises from complex, multi-layer interactions between diverse genetic and environmental factors. Genetic studies have identified multiple loci associated with tumor susceptibility. However, little is known about how germline polymorphisms interact with one another and with somatic mutations within a tumor to mediate acquisition of cancer traits. Here, we survey recent studies showing gene-gene...

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Share to Epistasis, Genetic
Share to Gastrointestinal Neoplasms
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 27588484
DOI: 10.18632/oncotarget.11701
PMCID: PMC5341900

Genes

MMP2
MUTYH
OGG1
PARP1
PRKAG2
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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