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Article

Examining the polymorphisms in the hypoxia pathway genes in relation to outcome in colorectal cancer.

PloS one - 1 Jan 2014

Haja Mohideen Asan M S, Hyde Angela, Squires Jessica, Wang Jing, Dicks Elizabeth, Younghusband Ban, Parfrey Patrick, Green Roger, Savas Sevtap

Abstract excerpt

INTRODUCTION: Colorectal cancer is a common malignancy. Identification of genetic prognostic markers may help prognostic estimations in colorectal cancer. Genes that regulate response to hypoxia and other genes that are regulated under the hypoxic conditions have been shown to play roles in cancer progression. In this study, we hypothesized that genetic variations in the hypoxia pathway genes were associated with...

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Identifiers

PMID: 25405996
DOI: 10.1371/journal.pone.0113513
PMCID: PMC4236175

Genes

CXCL12
LOX
MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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