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Article

Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer.

BMC medical genetics - 30 Apr 2012

Lascorz Jesus, Bevier Melanie, Schönfels Witigo V, Kalthoff Holger, Aselmann Heiko, Beckmann Jan, Egberts Jan, Buch Stephan, Becker Thomas, Schreiber Stefan, Hampe Jochen, Hemminki Kari, Försti Asta, Schafmayer Clemens

Abstract excerpt

BACKGROUND: Currently, the TNM classification of malignant tumours based on clinicopathological staging remains the standard for colorectal cancer (CRC) prognostication. Recently, we identified the mitochondrial oxidative phosphorylation chain as a consistently overrepresented category in the published gene expression profiling (GEP) studies on CRC prognosis. METHODS: We evaluated associations of putative...

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PMID: 22545919
DOI: 10.1186/1471-2350-13-31
PMCID: PMC3420261

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UQCRB

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