Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the Angiogenesis-Related Genes EFNB2, MMP2 and JAG1 Are Associated with Survival of Colorectal Cancer Patients.

International journal of molecular sciences - 29 Jul 2020

Scherer Dominique, Deutelmoser Heike, Balavarca Yesilda, Toth Reka, Habermann Nina, Buck Katharina, Kap Elisabeth Johanna, Botma Akke, Seibold Petra, Jansen Lina, Lorenzo Bermejo Justo, Weigl Korbinian, Benner Axel, Hoffmeister Michael, Ulrich Alexis, Brenner Hermann, Burwinkel Barbara, Chang-Claude Jenny, Ulrich Cornelia M

Abstract excerpt

An individual's inherited genetic variation may contribute to the 'angiogenic switch', which is essential for blood supply and tumor growth of microscopic and macroscopic tumors. Polymorphisms in angiogenesis-related genes potentially predispose to colorectal cancer (CRC) or affect the survival of CRC patients. We investigated the association of 392 single nucleotide polymorphisms (SNPs) in 33...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Jagged-1 Protein

Share to Matrix Metalloproteinase 2

Share to Neovascularization, Pathologic

Share to Odds Ratio

Share to Proportional Hazards Models

Source

Open in PubMed Open full text

Identifiers

PMID: 32751332
DOI: 10.3390/ijms21155395
PMCID: PMC7432124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the Angiogenesis-Related Genes EFNB2, MMP2 and JAG1 Are Associated with Survival of Colorectal Cancer Patients.PMID 32751332Read ↗

Differential expression of angiogenesis-related genes ‘VEGF’ and ‘angiopoietin-1’ in metastatic and EMAST-positive colorectal cancer patientsSemantic proximity Read ↗

Development of a novel angiogenesis-associated gene model for prognosis prediction in colorectal cancer.Semantic proximity Read ↗

Clinical implications of genetic variations in the VEGF system in relation to colorectal cancer.Semantic proximity Read ↗

Biomarkers of Angiogenesis in Colorectal CancerSemantic proximity Read ↗

VEGFA, FLT1, KDR and colorectal cancer: assessment of disease risk, tumor molecular phenotype, and survival.Semantic proximity Read ↗

Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients.Semantic proximity Read ↗

Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection.Semantic proximity Read ↗

Angiopoietin-2 gene polymorphisms are biomarkers for the development and progression of colorectal cancer in Han Chinese.Semantic proximity Read ↗

Biology and therapeutic implications of VEGF-A splice isoforms and single-nucleotide polymorphisms in colorectal cancer.Semantic proximity Read ↗

Genetic variants in VEGF gene family enhance colorectal cancer susceptibility via modulating metabolic pathways.Semantic proximity Read ↗

Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival.Semantic proximity Read ↗

Construction of a risk prediction model for colorectal cancer prognosis and immunotherapy based on angiogenesis-related geneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.