Article
Multilevel control of glucose homeostasis by adenylyl cyclase 8.
Diabetologia - 1 Apr 2015
Raoux Matthieu, Vacher Pierre, Papin Julien, Picard Alexandre, Kostrzewa Elzbieta, Devin Anne, Gaitan Julien, Limon Isabelle, Kas Martien J, Magnan Christophe, Lang Jochen
Abstract excerpt
AIMS/HYPOTHESIS: Nutrient homeostasis requires integration of signals generated by glucose metabolism and hormones. Expression of the calcium-stimulated adenylyl cyclase ADCY8 is regulated by glucose and the enzyme is capable of integrating signals from multiple pathways. It may thus have an important role in glucose-induced signalling and glucose homeostasis. METHODS: We used pharmacological and genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
