ADCY5 gene expression in adipose tissue is related to obesity in men and mice.

doi:10.1371/journal.pone.0120742

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Article

ADCY5 gene expression in adipose tissue is related to obesity in men and mice.

PloS one - 1 Jan 2015

Knigge Anja, Klöting Nora, Schön Michael R, Dietrich Arne, Fasshauer Mathias, Gärtner Daniel, Lohmann Tobias, Dreßler Miriam, Stumvoll Michael, Kovacs Peter, Blüher Matthias

Abstract excerpt

Genome wide association studies revealed an association of the single nucleotide polymorphism rs11708067 within the ADCY5 gene--encoding adenylate cyclase 5--with increased type 2 diabetes (T2D) risk and higher fasting glucose. However, it remains unclear whether the association between ADCY5 variants and glycemic traits may involve adipose tissue (AT) related mechanisms. We therefore tested the hypothesis that...

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Share to Adenylyl Cyclases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adipose Tissue

Share to Adiposity

Share to Diet, High-Fat

Share to Gene Expression Regulation, Enzymologic

Share to Glucose

Share to Insulin

Share to Quantitative Trait, Heritable

Source

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Identifiers

PMID: 25793868
DOI: 10.1371/journal.pone.0120742
PMCID: PMC4368112

Genes

ADCY5

Variants

rs11708067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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