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Article

Photo-sensitive degron variants for tuning protein stability by light.

BMC systems biology - 18 Nov 2014

Usherenko Svetlana, Stibbe Hilke, Muscò Massimiliano, Essen Lars-Oliver, Kostina Ekaterina A, Taxis Christof

Abstract excerpt

BACKGROUND: Regulated proteolysis by the proteasome is one of the fundamental mechanisms used in eukaryotic cells to control cellular behavior. Efficient tools to regulate protein stability offer synthetic influence on molecular level on a selected biological process. Optogenetic control of protein stability has been achieved with the photo-sensitive degron (psd) module. This engineered tool consists of the...

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Identifiers

PMID: 25403319
DOI: 10.1186/s12918-014-0128-9
PMCID: PMC4236813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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