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Article

High-throughput analysis of in vivo protein stability.

Molecular & cellular proteomics : MCP - 1 Nov 2013

Kim Ikjin, Miller Christina R, Young David L, Fields Stanley

Abstract excerpt

Determining the half-life of proteins is critical for an understanding of virtually all cellular processes. Current methods for measuring in vivo protein stability, including large-scale approaches, are limited in their throughput or in their ability to discriminate among small differences in stability. We developed a new method, Stable-seq, which uses a simple genetic selection combined with high-throughput DNA...

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Identifiers

PMID: 23897579
DOI: 10.1074/mcp.O113.031708
PMCID: PMC3820947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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