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Article

Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits.

Computational and mathematical methods in medicine - 1 Jan 2018

Wu Baolin, Pankow James S

Abstract excerpt

Multiple correlated traits are often collected in genetic studies. By jointly analyzing multiple traits, we can increase power by aggregating multiple weak effects and reveal additional insights into the genetic architecture of complex human diseases. In this article, we propose a multivariate linear regression-based method to test the joint association of multiple quantitative traits. It is flexible to...

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PMID: 29743933
DOI: 10.1155/2018/2564531
PMCID: PMC5878919

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