Article
Anti-phospholipase A2 receptor antibodies and the pathogenesis of membranous nephropathy.
Nephron. Clinical practice - 1 Jan 2014
Ronco Pierre, Debiec Hanna
Abstract excerpt
Since the early 2000s, considerable advances have been achieved in the understanding of molecular pathomechanisms of human membranous nephropathy (MN), inspired by studies of Heymann nephritis, a faithful experimental model. These studies led to the identification of neutral endopeptidase, the type-M phospholipase A2 receptor (PLA2R), and cationic bovine serum albumin as target antigens of circulating and...
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