Article
[Anti-NEP and anti-PLA2R antibodies in membranous nephropathy: an update].
Revue medicale de Bruxelles - 1 Jan 2000
Pozdzik A A, Debiec H, I Brochériou, Husson C, Rorive S, Broeders N, Le Moine A, Ronco P, Nortier J
Abstract excerpt
Membranous nephropathy (MN) is the most common cause for nephrotic syndrome in adults and occurs as an idiopathic (primary) or secondary disease. Since the early 2000's, substantial advances have been made in the understanding of the molecular bases of MN. The neutral endopeptidase (NEP) and the receptor for secretory phospholipase A2 (PLA2R) have been identified as target antigens for circulating and deposited...
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