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Mechanisms of Primary Membranous Nephropathy

30 Mar 2021

Abstract excerpt

Membranous nephropathy (MN) is an autoimmune disease of the kidney glomerulus and one of the leading causes of nephrotic syndrome. The disease exhibits heterogenous outcomes with approximately 30% of cases progressing to end-stage renal disease. The clinical management of MN has steadily advanced owing to the identification of autoantibodies to the phospholipase A2 receptor (PLA2R) in 2009 and thrombospondin...

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PMID: 33808418
DOI: 10.3390/biom11040513

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