Article
Idiopathic membranous nephropathy and IgG4: an interesting relationship.
Clinical nephrology - 1 Jul 2014
Filippone Edward J
Abstract excerpt
Idiopathic membranous nephropathy (iMN) is a single-organ autoimmune disease characterized by subepithelial deposition of immune complexes containing IgG4 resulting in proteinuria, nephrotic syndrome, and, in some, end-stage renal disease. The pathogenesis involves a chronic IgG4 response against specific podocyte antigens which have now been at least partially defined in the neonatal, early childhood, and adult...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
