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Article

Membranous nephropathy: current understanding of various causes in light of new target antigens

21 Jan 2021

Abstract excerpt

PURPOSE OF REVIEW: Membranous nephropathy is an autoimmune disease caused by antibodies mostly directed to podocyte antigens. PLA2R and THSD7A antigens were described in 2009 and 2014 using classical immunochemical techniques. In the last 2 years, thanks to the combination of laser microdissection of glomeruli and mass spectrometry of solubilized digested proteins, several antigens associated with various causes...

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PMID: 33480620
DOI: 10.1097/mnh.0000000000000697

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