Fine mapping and candidate gene search of quantitative trait loci for growth and obesity using mouse intersubspecific subcongenic intercrosses and exome sequencing.

doi:10.1371/journal.pone.0113233

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Article

Fine mapping and candidate gene search of quantitative trait loci for growth and obesity using mouse intersubspecific subcongenic intercrosses and exome sequencing.

PloS one - 1 Jan 2014

Ishikawa Akira, Okuno Sin-ichiro

Abstract excerpt

Although growth and body composition traits are quantitative traits of medical and agricultural importance, the genetic and molecular basis of those traits remains elusive. Our previous genome-wide quantitative trait locus (QTL) analyses in an intersubspecific backcross population between C57BL/6JJcl (B6) and wild Mus musculus castaneus mice revealed a major growth QTL (named Pbwg1) on a proximal region of mouse...

Topics

Alleles
Animals
Antigens, CD
Body Weight
Chromosome Mapping
Crosses, Genetic
Exome
Female
Genotype
Integrin beta Chains
Lectins, C-Type
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C57BL

Minor Histocompatibility Antigens

Obesity

Phenotype

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 25398139
DOI: 10.1371/journal.pone.0113233
PMCID: PMC4232600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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