Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2.

BMC genomics - 23 Jan 2015

Gularte-Mérida Rodrigo, Farber Charles R, Verdugo Ricardo A, Islas-Trejo Alma, Famula Thomas R, Warden Craig H, Medrano Juan F

Abstract excerpt

BACKGROUND: Mouse chromosome 2 is linked to growth and body fat phenotypes in many mouse crosses. With the goal to identify the underlying genes regulating growth and body fat on mouse chromosome 2, we developed five overlapping subcongenic strains that contained CAST/EiJ donor regions in a C57BL/6J (hg/hg) background (hg is a spontaneous deletion of 500 Kb on mouse chromosome 10). To fine map QTL on distal mouse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Binding Sites

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Body Weight

Share to Chromosomes

Share to Genetic Linkage

Share to MicroRNAs

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 25613955
DOI: 10.1186/s12864-014-1191-8
PMCID: PMC4308015

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2.PMID 25613955Read ↗

Fine mapping and candidate gene search of quantitative trait loci for growth and obesity using mouse intersubspecific subcongenic intercrosses and exome sequencing.Semantic proximity Read ↗

Dissection of a genetically complex cluster of growth and obesity QTLs on mouse chromosome 2 using subcongenic intercrosses.Semantic proximity Read ↗

Fine mapping reveals sex bias in quantitative trait loci affecting growth, skeletal size and obesity-related traits on mouse chromosomes 2 and 11.Semantic proximity Read ↗

A wild derived quantitative trait locus on mouse chromosome 2 prevents obesity.Semantic proximity Read ↗

A proximal genomic region of mouse chromosome 10 contains quantitative trait loci affecting fatness.Semantic proximity Read ↗

Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2.Semantic proximity Read ↗

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels.Semantic proximity Read ↗

Adiposity QTL <i>Adip20</i> decomposes into at least four loci when dissected using congenic strainsSemantic proximity Read ↗

Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains.Semantic proximity Read ↗

Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight.Semantic proximity Read ↗

Fine mapping of quantitative trait loci affecting organ weights by mouse intersubspecific subcongenic strain analysis.Semantic proximity Read ↗

A high-resolution association mapping panel for the dissection of complex traits in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.