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Article

Fine mapping reveals sex bias in quantitative trait loci affecting growth, skeletal size and obesity-related traits on mouse chromosomes 2 and 11.

Genetics - 1 Jan 2007

Farber Charles R, Medrano Juan F

Abstract excerpt

Previous speed congenic analysis has suggested that the expression of growth and obesity quantitative trait loci (QTL) on distal mouse chromosomes (MMU) 2 and 11, segregating between the CAST/EiJ (CAST) and C57BL/6J-hg/hg (HG) strains, is dependent on sex. To confirm, fine map, and further evaluate QTL x sex interactions, we constructed congenic by recipient F2 crosses for the HG.CAST-(D2Mit329-D2Mit457)N(6)...

Read the complete abstract on PubMed

Topics

Animals
Body Weight
Chromosome Mapping
Chromosomes
Crosses, Genetic
Female
Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Growth

Male

Mice

Mice, Inbred C57BL

Obesity

Phenotype

Prejudice

Quantitative Trait Loci

Quantitative Trait, Heritable

Skeleton

Source

Open in PubMed Open full text

Identifiers

PMID: 17110492
DOI: 10.1534/genetics.106.063693
PMCID: PMC1775020

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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