Article
Fine mapping of quantitative trait loci affecting organ weights by mouse intersubspecific subcongenic strain analysis.
Animal science journal = Nihon chikusan Gakkaiho - 1 Apr 2013
Mollah Md Bazlur Rahman, Ishikawa Akira
Abstract excerpt
The genetic architecture of organ weights is not well understood. In this study, we fine-mapped quantitative trait loci (QTLs) affecting organ weights by characterizing six intersubspecific subcongenic mouse strains with overlapping and non-overlapping genomic regions on chromosome 2 derived from wild Mus musculus castaneus. QTLs for heart, lung, spleen and kidney weights were revealed on a 6.38-Mb genomic region...
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