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Article

Discovery and refinement of muscle weight QTLs in B6 × D2 advanced intercross mice.

Physiological genomics - 15 Aug 2014

Carbonetto P, Cheng R, Gyekis J P, Parker C C, Blizard D A, Palmer A A, Lionikas A

Abstract excerpt

The genes underlying variation in skeletal muscle mass are poorly understood. Although many quantitative trait loci (QTLs) have been mapped in crosses of mouse strains, the limited resolution inherent in these conventional studies has made it difficult to reliably pinpoint the causal genetic variants. The accumulated recombination events in an advanced intercross line (AIL), in which mice from two inbred strains...

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Identifiers

PMID: 24963006
DOI: 10.1152/physiolgenomics.00055.2014
PMCID: PMC4137148

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Source receipt: pubmed, retrieved 7 Sept 2026.

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