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Article

Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains.

PloS one - 1 Jan 2017

Lin Cailu, Fesi Brad D, Marquis Michael, Bosak Natalia P, Lysenko Anna, Koshnevisan Mohammed Amin, Duke Fujiko F, Theodorides Maria L, Nelson Theodore M, McDaniel Amanda H, Avigdor Mauricio, Arayata Charles J, Shaw Lauren, Bachmanov Alexander A, Reed Danielle R

Abstract excerpt

An average mouse in midlife weighs between 25 and 30 g, with about a gram of tissue in the largest adipose depot (gonadal), and the weight of this depot differs between inbred strains. Specifically, C57BL/6ByJ mice have heavier gonadal depots on average than do 129P3/J mice. To understand the genetic contributions to this trait, we mapped several quantitative trait loci (QTLs) for gonadal depot weight in an F2...

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PMID: 29194435
DOI: 10.1371/journal.pone.0188972
PMCID: PMC5711020

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Source receipt: pubmed, retrieved 7 Sept 2026.

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