Article
A wild derived quantitative trait locus on mouse chromosome 2 prevents obesity.
BMC genetics - 23 Sept 2010
Mollah Md Bazlur R, Ishikawa Akira
Abstract excerpt
BACKGROUND: The genetic architecture of multifactorial traits such as obesity has been poorly understood. Quantitative trait locus (QTL) analysis is widely used to localize loci affecting multifactorial traits on chromosomal regions. However, large confidence intervals and small phenotypic effects of identified QTLs and closely linked loci are impeding the identification of causative genes that underlie the QTLs....
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