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Article

Genetic variation in imprinted genes is associated with risk of late-onset Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Chaudhry Mamoonah, Wang Xingbin, Bamne Mikhil N, Hasnain Shahida, Demirci F Yesim, Lopez Oscar L, Kamboh M Ilyas

Abstract excerpt

Epigenetic changes including genomic imprinting may affect risk of late-onset Alzheimer's disease (LOAD). There are >100 known imprinted genes and most of them are expressed in human brain. In this study, we examined the association of single nucleotide polymorphisms (SNPs) in 93 imprinted genes with LOAD risk in 1291 LOAD cases and 958 cognitively normal controls. We performed single-site, gene-based, and...

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Source

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Identifiers

PMID: 25391383
DOI: 10.3233/JAD-142106
PMCID: PMC4324355

Genes

DLGAP2
GRB10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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